General Cell Based Assays
Cayman Chemical nTosIs Imagng asy KIt 96Wel
Cayman’s NETosis Imaging Kit provides a simple staining protocol for visualizing the process of NETosis kinetically ex vivo and in vitro. A cell-permeable DNA dye allows visualization of the dynamic changes of the nucleus during the process of NETosis, while a cell-impermeable dye detects the extruded DNA. Combining the fluorescence visualization of these dyes with brightfield imaging in a high-content platform allows for exquisite differentiation between different modes of cell death. The amount of EAch reagent provided is sufficient for two 96-well plates.
Cayman Chemical FFA asy Sample Buffer 1ea
A PROTAC that drives Cdk2 degradation selectively degrades Cdk2 (IC50 24 nM) over seven additional CDKs at 500 nM but also degrades Aurora A kinase and IKZF1 at 250 nM reduces Cdk2 levels and increases the percentage of cells expressing CD11b a marker of differentiation in primary AML cells decreases proliferation without reducing the viability of as well as induces differentiation in primary HSCs
Abcam Rhod-4 Calcium Assay Kit - No Wash
Rhod-4 Calcium Assay Kit - No Wash
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ALDH Cofactr 3mg
A B2-AR agonist selectively induces cAMP accumulation in CHO cells expressing the B2-AR over the B1- and B3-ARs (EC50s 0.4 398 and 794 nM for the human receptors respectively) inhibits contractions induced by electrical stimulation in isolated superfused guinea pig trachea strips inhibits histamine-induced bronchospasms in guinea pigs when administered via nebulization (EC50 30 UM)
Cayman Chemical MPO asy Buffer1X 1ea
A - and K1-opioid receptor antagonist (Kis 0.3 and 0.2 nM respectively) selective for - and K1-opioid receptors over the -opioid receptor (Ki 12.8 nM) reversibly inhibits electricity-induced twitches of isolated guinea pig ileal longitudinal muscle strips (IC50 48 nM) indicating opioid agonist activity inhibits endomorphin 1-induced conditioned place preference in mice at 0.3 UG/animal i.c.v. prevents decreases in urine output induced by fentanyl D-propoxyphene buprenorphine profadol or bromadoline in water-loaded rats at 40 mg/kg reduces hemokinin 1-induced increases in the latency to withdrawal in the tail-flick test in mice
Hampton Research HR2-137/MembFac HT - 1 ml, Deep Well block format
HR2-137/MembFac HT - 1 ml, Deep Well block format. Please note items from this supplier are non-returnable.
EDITCO BIO INC Human CRISPRevolution Controls Kit
A simplified easy-to-use kit designed for users to optimize their transfection protocols & become familiar with Synthego’s chemically modified sgRNAs and CRISPR/Cas9 technology.
Aat Bioquest Cell Explorer Live Cell Tracking Kit Red Fluorescence (200 Tests)
Our Cell Explorer fluorescence imaging kits are a set of tools for labeling cells for fluorescence microscopic investigations of cellular functions. This catalog is for 200 Tests.
Cayman Chemical THUNDRPhosphop38a MAPK 9600Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-p38αβγ MAPK14/11/12 (T180/Y182) in cell lysates
Cayman Chemical GlutathIon Reductase asy K 96
GR is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized GSSG to GSH. This enzyme is essential for the GSH redox cycle which maintains adequate levels of reduced cellular GSH. A high GSH/GSSG ratio is essential for protection against oxidative stress. Cayman’s Glutathione Reductase Assay Kit measures GR activity by measuring the rate of NADPH oxidation. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in the absorbance at 340 nm is directly proportional to the GR activity in the sample.
Eurofins Discoverx InCELL Hunter eXpress Bcl2L1-Bax Protein Binding Assay, 2-plate Kit. (96-0009E3CP16M)
The InCELL Hunter eXpress Bcl2L1-Bax Protein Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that disrupt protein binding. This kit assesses compound-based disruption of Bcl2L1-Bax binding via detection of Bax levels. This product uses EFC technology. The cell line included overexpresses Bcl2L1 target in an untagged form and Bax binding partner fused to ProLabel. When a compound engages the Bcl2L1 target protein, partner binding is disrupted and the destabilized Bax is degraded, leading to a loss of EFC signal upon addition of EA containing detection reagent. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Signaling Technology BrdU Cell Proliferation Chemiluminescent Assay Kit 1 Kit
BrdU Cell Proliferation Chemiluminescent Assay Kit 1 Kit